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Table 1 Impact of the COVID-19 pandemic on level and quarterly trend changes in hospital consumption of linezolid and combined Vancomycin/Teicoplanin (DDD/1000 Patient-Days) in a tertiary hospital in Alexandria, Egypt from 2019 to 2023

From: Evaluating anti-MRSA antibiotic stewardship with a focus on trends in consumption and resistance in a tertiary hospital in Alexandria, Egypt from 2019 to 2023

Term

Hospital Linezolid consumption (DDD/1000PD)

Hospital combined Vancomycin/Teicoplanin consumption (DDD/1000PD

β (95% CI)

β (95% CI)

(Intercept)

-5.76 (-57.43, 45.90)

8.60 (-16.5, 33.70)

Quarterly trend before COVID-19

5.17 (-10.40, 20.75)

2.86 (-4.71, 10.43)

Level change after COVID-19

95.64 (49.03, 142.26)*

22.15 (-0.50, 44.79)

Quarterly trend change after COVID-19

-7.86 (-23.71, 8.00)

-2.99 (-10.69, 4.72)

  1. DDD: Defined Daily Doses. PD: Patient Days. β: regression coefficient representing change in DDD/1000 patient-days. CI: confidence interval. *Statistically significant (p < 0.05)