Table 2 Overview of the included companies and their digital health interventions for depression
DHID | Provider | Funding (Million USD) | Target population | Psychological Intervention | Services provided | Other novel technologies (e.g., CAs, EMA, Sensing) | Operating System | Country & language(s) | Total No of publications |
|---|---|---|---|---|---|---|---|---|---|
Lyra Health | Lyra Health, Inc. | 910 | EAP, Employees | CBT, ACT, DBT, ET, UP, Mindfulness | - Face-to-face support - Remote support (Video therapy, txt-based, phone (crisis intervention)) - Self-guided components | --- | Not an app (website) | U.S. (English) | 3 |
Ginger | Ginger.io, Inc | 220 | EAP, Employees | CBT, Mindfulness | - Remote support (Video therapy, txt-based) - Self-guided components | EMA, Mood tracker | Android, iOS | U.S. (English) | 3 |
Quartet | Quartet Health Inc | 219 | Health insurance, health providers | CBT | - Face-to-face - Remote support (Video therapy, Online-platform) | --- | iOS | U.S. (English) | 0 |
Vida Health | Vida Life Inc | 188 | EAP, Employees | CBT, Mindfulness | - Remote support (Video therapy, txt-based) - Self-guided components | --- | Android, iOS | U.S. (English) | 2 |
Modern Health | Modern Health, Inc. | 167 | EAP, Employees | CBT | - Remote support (Video therapy, txt-based, live-community) - Self-guided components | --- | Android, iOS | U.S. (English) | 0 |
Mind strong | Mindstrong Health | 159 | EAP, health insurance, health providers | CBT, Crisis management | - Remote support (Video therapy, phone, txt-based, measurements in the mobile app) | Digital biomarkers | Android, iOS | U.S. (English) | 0 |
Happify | Happify, Inc. | 118 | General population | CBT, PP, ACT, DBT, PST, IPT, BA, ET, MBSR, crisis intervention | - Self-guided components - Gamification - Online-community | Biofeedback HRV, breathing. Conversational Agent | Android, iOS | U.S. (English, French, Chinese, Japanese, Spanish, German, Portuguese, Italian) | 6 |
Woebot* | Woebot Health | 113 | General population | CBT, DBT, IPT, Mindfulness | - Self-guided components | EMA, Mood tracker. Conversational Agent | Android, iOS | U.S. (English) | 2 |
Deprexis | Orexo | 73 | Health insurance, clinical population | CBT, BA, IPT, SFT, MBCT, relaxation, Physical activity and lifestyle modification (exercise and nutrition), SFC, PP, Dreamwork and EFT | - Remote support (Video) - Self-guided components | --- | Not an app (website) | Sweden (English, German, Spanish, Greek, French, Italian, European Portuguese, and Swedish) | 16 |
Unmind | Unmind Ltd. | 63 | EAP, Employees | CBT, PP, ACT, MBCT | - Remote support (helplines and local healthcare providers) - Self-guided components | EMA, Mood tracker. Conversational Agent | Android, iOS | UK (English) | 1 |
Meru Health | Meru Health | 51 | EAP, Employees, health providers, Health insurance | CBT, BA, MBCT, MBSR, Holistic intervention (sleep, nutrition, habits) | - Remote support (phone, chat-based coach support, virtual workshops) - Online-community | Biofeedback and HRV with a wearable device | Android, iOS | U.S. (English) | 9 |
Koa Health/Mindset | Koa Health B.V | 44 | Healthcare, Health insurance, EAP | CBT, PP, Mindfulness | - Remote support (Video therapy, txt-based) - Self-guided components | – | iOS, website | Spain (English) | 0 |
NeuroFlow | NeuroFlow, Inc. | 31 | Government, military population, health providers | CBT, DBT, ET, Mindfulness | - Remote support (Video therapy) - Self-guided components | Track behaviours (sleep, activity, mood, stress and pain) | Android, iOS | U.S. (English) | 3 |
Brightside Health | Brightside Health Inc. | 31 | (EAP) Employees, health providers | CBT | - Remote support (Video therapy, txt-based) | – | Not an app, Website | U.S. (English) | 0 |
Limbix | Limbix Health Inc. | 31 | Adolescents (13–22 years old) | Psychoeducation, CBT, BA, PST, Mindfulness | - Remote support (Video therapy) - Self-guided components | EMA, Mood tracker, Conversational Agent | Android, iOS | U.S English | 0 |
Spring Health | Spring Care, Inc. | 29 | EAP | CBT, Mindfulness, Holistic intervention (exercise, diet, sleep) | - Remote support (Video therapy) - Face-to-face support - Self-guided components | EMA, Mood tracker | Android, iOS | U.S. English | 0 |
Valera Health | Valera Health | 26 | General population, clients of insurance companies and health providers | CBT, Mindfulness, Psychoanalysis | - Remote support (Video therapy) - Self-guided components | - | Android, iOS | U.S. English, (Spanish, simplified Chinese) | 1 |
Space from depression/Anxiety | Silver Cloud Health | 26 | EAP, clients of insurance companies and health providers | CBT, BA, PP, ET, Mindfulness | - Remote support (txt-based) - Self-guided components | EMA, Mood tracker | Android, iOS and website | U.S. English Spanish German | 17 |
Learn to Live | Learn to Live, Inc. | 15 | EAP, insurance companies and health providers, students | CBT | - Remote support (Video therapy, phone, txt-based). - Self-guided components | - | Not an app (website) | U.S. English | 0 |
Mindler | Mindler AB | 13 | General population | CBT | - Remote support (Video therapy, txt-based chat) - Self-guided components | - | Android, iOS | Sweden Swedish / English | 0 |
Wysa* | Wysa Ltd. | 9.3 | General population, EAP | CBT, DBT, Mindfulness | - Remote support (Txt-based chat) - Self-guided components | Conversational Agent | Android, iOS | India (English, Hindi, Punjabi & Bengali) | 2 |
Kintsugi Hello | Kintsugi Mindful Wellness, Inc. | 9.0 | General population | CBT, DBT | - Self-guided components - Community support | Voice biomarker for detection | iOS | U.S English, Spanish | 0 |
HelloBetter | Geton-institut.de | 9.0 | General population, clients of certain insurance companies | CBT, BA, PST, healthy sleeping, physical activity | - Remote support (Video therapy) - Self-guided components | EMA, Mood tracker | Android, iOS -Website | Germany English, German | 13 |
Shine* | Shine, Inc. | 8.2 | General population, EAP. | ACT, Mindfulness | - Self-guided components -Community support (monthly virtual workshops) | EMA, Mood tracker (only in the premium version). Conversational Agent | Android, iOS | U.S. English | 0 |
My Online Therapy | Lekta Therapy Ltd. | 6.0 | General population | CBT, ACT, DBT, IPT, CAT, Couple therapy, EMD, MBCT, | - Remote support (Video therapy) - Self-guided components | Conversational Agent | Website + app Android, iOS | UK English | 0 |
myStrength | myStrength, Inc. | 5.8 | people under certain EAP and health providers | CBT, PP, ACT, Mindfulness | - Remote support (Video therapy) - Self-guided components | - | Android, iOS | US English | 4 |
InnerHour | InnerHour | 5.6 | General population, EAP. | CBT, PP, Mindfulness, ACT, physical activity | - Remote support (Video therapy) - Self-guided components | EMA (mood tracker). Conversational Agent | Android, iOS | India English | 0 |
wayForward | PsyInnovations Inc | 4.7 | General population, EAP, and health providers | CBT, PP, DBT, Mindfulness | - Remote support (text-based, phone) - Self-guided components | - | Android, iOS | US English | 0 |
Mindoula | Mindoula Health, Inc. | 4.2 | Comorbid conditions and clinical population, health providers | CBT | - Face-to-face support - Remote support (Video therapy, phone) - Self-guided components | EMA (mood tracker) | Android, iOS | US English, Spanish | 0 |
Youper AI Therapy | Youper, Inc. | 3.5 | Students, general population, health insure companies | CBT, ACT, DBT, PST, MBCT | - Remote support (Video therapy) - Self-guided components | Conversational agent | Android, iOS | U.S English | 0 |
Total | 2,592 | Â | Â | Â | Â | Â | Â | 83 | |